NIH Joint Development of a Closed Loop System for Blood Glucose Control

Dexcom and Tandem Diabetes Care, which specialize in diabetes, are working with digital health company TypeZero Technologies to develop a closed-loop system for blood glucose control.

The system will include Dexcom's G5 glucose sensor, tandem insulin pump and smartphone, which will run TypeZero's inControl closed-loop algorithm. According to the statement, the joint platform will continue to detect blood sugar levels and automatically adjust the delivery of insulin. While the primary purpose of the system is to modulate the base or inject insulin, the system is also capable of automating the correction and may also allow the user to autonomously replenish the corresponding dose of insulin prior to the meal. It will be tested in the International Diabetes Closed Loop trial, which is funded by the National Institutes of Health (NIH) and will begin later this year. The experimenter hopes to recruit 240 adult patients with type 1 diabetes for the trial.

Boris Kovatchev, director and lead researcher at the University of Virginia Diabetes Technology Center, said: "The IDCL trial is a key experiment in a closed-loop control system, including seven institutions from the US led by the University of Virginia and three European institutions. In the trial, Tandem, Dexcom and TypeZero provided related technology integration, which represents a new level of development in artificial pancreas research and development."

NIH Joint Development of a Closed Loop System for Blood Glucose Control

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