Xinhua News Agency, Kyoto University, Japan, induced pluripotent stem cell (iPS cell) research institute recently announced that the researchers used iPS cells to cultivate a "killer T cell" that can target cancer cells, making it practical for cancer immunotherapy. further.
T cells are an immune cell, the main force in the immune system and viruses and cancer cells, also known as "killer T cells." Researchers at Kyoto University have successfully used iPS cells to grow a large number of T cells a few years ago, but these T cells not only attack cancer cells, but also attack normal cells.
To this end, the researchers used genetic technology to modify the genes in iPS cells and successfully cultured T cells that attack only cancer cells. The effect has been confirmed in mouse experiments.
Researchers say this is one of the important results in improving the safety and effectiveness of cancer immunotherapy. The related papers have been published in the online edition of Cell-Stem Cell.
The principle of cancer immunotherapy is to use the body's own immune system to kill cancer cells. One method is to in vitro culture T cells that can target cancer cells, and then inject them into patients, but the cost is higher.
iPS cells are stem cells that are "reprogrammed" by mature somatic cells and have similar differentiation potential to embryonic stem cells. Researchers at Kyoto University said that the use of iPS cells to culture T cells is more efficient and is expected to reduce the cost of immunotherapy. (Hua Yi)
Source: Xinhua News Agency
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