The Japanese government has recently approved a clinical trial plan for the use of induced pluripotent stem cells (iPS cells) to treat Parkinson's disease at Kyoto University, Japan, which will be the first time iPS cells have been used to treat human Parkinson's disease.
Induced pluripotent stem cells are stem cells that are "reprogrammed" by mature somatic cells and have similar differentiation potential to embryonic stem cells. The iPS Cell Research Institute of Kyoto University proposes to use iPS cells to culture neural precursor cells, and then transplant these precursor cells capable of differentiating into nerve cells into the brain of patients with Parkinson's disease to test the effectiveness of this method in the treatment of Parkinson's disease. Sex and safety. The school's researchers have confirmed in animal tests that this method can improve the symptoms of Parkinson's disease in monkeys.
Japan’s current affairs agency reported on the 30th that the Japanese government approved the clinical trial plan on the 29th. The research team will recruit several patients with poorly treated Parkinson's disease to participate in the trial, and will announce specific plans in the near future. Previously, the Japanese government approved the use of iPS cells to treat eye diseases and heart disease.
Parkinson's disease is a degenerative disease of the nervous system. The main pathological change is the death of nerve cells secreting dopamine in the brain. The clinical manifestations include hand and foot tremor, body stiffness, and slow movement. There is no cure.
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