Author: Sun Kwok-kan Huang Xin Release Date: 2019-01-18
The Shanghai Orthokeratology research team led by Prof. Zhou Xingtao and Xue Feng, the attending physician of Fudan University, has found that Orthokeratology combined with low-concentration atropine eye drops can significantly control the development of myopia. Related research results have recently been published in the latest issue of the international academic journal Contact Lens & Anterior Eye, which has attracted wide attention from both domestic and foreign counterparts.
It is reported that juvenile myopia is mostly axial myopia with axial growth. If the axial growth is too fast, it indicates that myopia speed is growing too fast and myopia is deepening too fast. At present, it is recognized that there are three effective ways to control the development of myopia, such as outdoor activities, optical methods (including OK mirror) and low concentration atropine eye drops. Among them, the effect of OK mirror on low-to-moderate adolescent myopia was different in different reports. Compared with single-lens frame lenses, the average eye axis growth was 41.7%. It can be seen that there are still many wearers who can not control the development of myopia well; and the low concentration of atropine has better myopia control effect and less drug side effects according to previous reports.
Zhou Xingtao and Xue Feng's research team pioneered innovative ideas. Do they want to achieve better control of myopia if they use optical and drug combinations?
Therefore, the team performed a retrospective study of 3-year axial length growth in 60 eyes of 60 subjects who had completed two years of Orthokeratology. The study subjects were between 5.6 and 11.6 years of age who started treatment with OK, with an average of approximately 275 degrees. In their first year of treatment with OK mirror (stage I), their annual axial growth exceeded 0.25 mm; in the second year (phase II), in addition to OK mirror treatment, they used 0.01% atropine eye drops per night. Combined treatment for one year. The team then compared the length of the axial length before and after the drug treatment. The results showed that the average axial growth rate of the stage I subjects was 0.46 mm per year. After the phase II combined with atropine treatment, the axial growth was significantly reduced. 0.14 mm per year.
The researchers concluded that in the fast-growing youth population of myopia, if the OK-mirror treatment is still unable to control rapid axial growth, the addition of low-concentration atropine can significantly slow the axial growth rate of patients treated with OK. Enhance the effect of myopia control, and this effect has nothing to do with basic myopia and age. This will benefit more from the addition of low-dose atropine in patients with an eye axis that grows too fast after OK mirror treatment.
The researchers also confirmed that after OK mirror treatment, myopia control is still poor, or the rapid growth of myopia (such as children with low age, high myopia in both parents), combined treatment is better than single treatment control.
Experts said that the study provides a strong evidence-based basis for clinical combined treatment of myopia and personalized control of myopia.
Source: Science Network
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